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Post-doc Research Associate

 

Job Description

This post will be based in the Immunology Group headed by Mr Wayel Jassem and Dr Yun Ma at the Institute of Liver Studies (ILS) at the King’s College Hospital and King’s College London, Denmark Hill campus. The post holder will be focused on one project: 



To perform liver transplantation related research project entitled: Assessing the effect of Andrographolide (Andro) on fatty liver graft in the setting of ex-situ normothermic machine perfusion: Andro is a botanical compound which has a potent anti-inflammatory property by inhibiting NF-κB, Nrf2 activation and in reducing fat content of liver in animal model. The candidate will collect hepatic mononuclear lymphocytes in liver perfusate and set up cell culture after adding different doses of Andro. Once the explanted fatty liver tissue is available, the immune cells within the liver tissue will be isolated to culture after adding Andro. The effect of Andro on immune cells will be assessed using FACs technique (multiple parameter flow cytometry and advanced flow cytometry data analysis). The co-culture of Andro treated immune cells with primary hepatocytes will be performed. The candidate should also have a strong background in molecular biology techniques (CRISPR/Cas9 editing tools, gene expression, ChIP, etc.), since the impact of Andro on gene expression will be assessed by RNA-seq, ChIP-seq analyses etc.



The candidate will also be involved in the training and supervision of PhD students and undergrade BSc students who are involved in related research projects.



This post is a fixed-term contract with the possibility to further extension, being a part-time post: 10.5 hours per week.



Qualifications

 




  • PhD or equivalent level in Immunology, including transplantation immunology and tumour immunology

  • Expertise in blood processing, liver tissue processing, T cell and B cell immunology in human beings

  • Willingness to work as part of a team, to collaborate and help other colleagues when necessary

  • Excellent verbal and written communication skills



Skills

 




  • Having performed or mastered followng techniques: molecular biology techniques (RNA isolation, gene expression analysis, plasmid isolation, bacterial transformation), multiple parameter flow cytometry experimental setup and analysis

  • Gene silencing and activation on primary Tregs and Teffs cells (shRNA and/or CRISPR/Cas9 editing tools)

  • Statistical analysis of data



 




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Research assistant required to work on a project that investigates the higher education experiences and outcomes for mixed-heritage/raced young people (18-25yrs) in London. The project is a mixed-method study consisting of quantitative data analysis of existing public survey datasets, focus groups with mixed-heritage students in London universities, sixth-forms and colleges, and semi-structured interviews with school and university staff. The study is led Dr Ayo Mansaray (School of Education, Communication and Society) with Dr Chiamaka Nwosu (King?s Business School).

The post-holder will provide research support for the qualitative elements of the project, including tasks such as: recruitment and arrangement of student and staff interviews, contributing to the drafting of qualitative interview topic guides, conducting student focus groups and one-to-one staff interviews, data management (e.g. cataloguing data files, sending files for transcription etc.), data analysis, and report writing. The RA will also provide ad hoc administrative support to the project team. The RA will be expected to attend in-person project meetings with funders in London.



Qualifications

BA and MA/MSC in a Social Science/Arts & Humanities discipline, undertaking a doctorate.



Skills

Experience of MS Teams, and MS office suite (e.g. Word etc.),  and knowledge of bibliographic software (e.g. Endnote) and qualitative data analysis software (e.g. Nvivo). 

Interest in the experiences of racialised groups in the education system and/or social justice in education. 

Understanding of research design and project management. Good understanding of qualitative methodologies, specifically prior experience of focus group or individual interviewing. 

Good communication, organisational and interpersonal skills. 

Ability to travel across London to attend meetings and conduct interviews. 

We are looking for an enthusiastic technician to join our team of scientists and clinicians to develop bone marrow organoids and investigate the interaction between malignant cells and the immune system. The successful candidate will work with fresh and frozen peripheral blood and bone marrow samples from healthy donors and patients with myeloproliferative neoplasm. 

The Research technician needs to use a variety of techniques such as flow cytometry, cell culture, imaging and other necessary techniques. 



Qualifications

A degree in biology or an equivalent degree in a relevant subject.



Skills

Essential:

Experience in cell culture, flow cytometry, and work with organoids.

Familiar with essential molecular techniques.

 

NOT SUITABLE FOR STUDENTS

Job purpose 

To work as part of either the Recruitment or the HR Operations Services Team to provide a quality, timely, customer focused HR recruitment/contractual administration/transactional service to key stakeholders, job applicants and customers throughout the Queen Mary community.

To assist with a range of administrative support appropriate to the grade and as required within the HR team, by managers and employees, abiding by all HR policies and procedures and making sure key associated tasks are delivered, including maintenance of records. 

To operate as an effective and flexible member of the HR team, supporting the work of the department in the delivery of an effective HR service to line managers, staff and prospective job applicants.

 

Main duties and responsibilities 

To provide a high level of customer service to all customers, including staff at the University and job applicants 

To support the Recruitment or HR Operations function to help provide high quality HR administrative support. Duties will include: 

o Recruitment administration 

o Asylum & Immigration Documentation checks for New Starters/Re-Joiners/Lifecycle of Employee/ Extensions/Annual Right to Work checks o General HR administration 

o Administration of employment administration o ResourceLink/Payroll updates 

o Administration support providing letters for grading of posts 

o Probation administration o Administration of Parental Leave 

o Termination of employment (all categories) 

o Upkeep of electronically stored personal records 

o Compliance with Data Protection Legislation

To provide accurate and timely information to members of staff in the wider University. 

To apply a good working knowledge of administrative processes to answer queries and resolve problems from colleagues and external customers. 

To manage own workload allocated by the Recruitment or HR Operations Team Leader ensuring that all queries are dealt with in a timely, accurate manner, escalating complex problems to the relevant senior colleague as required. 

To input and make revisions to electronic systems and produce contractual and other documentation within defined quality standards and service level agreements. 

To follow published procedures and work instructions where supplied, using appropriate judgement as to when to escalate an unusual enquiry to the Recruitment or Employment Administration Services Team Leader. 

To ensure that all written documentation e.g., e-mail, letters, contracts are accurate and contains the correct information. 

To work across the wider Recruitment and HR Operations Team, in response to peaks and troughs of business activity and to provide additional HR administrative support for seasonal activities such as e.g., the processing of Student Ambassador, Demonstrator, Teaching Assistant and Teaching Fellow and other short term engagements. 

To provide information and guidance on administrative processes to any new members of staff in the department. 

Ensure that electronic filing is carried out promptly, securely and accurately

To maintain confidentiality in all matters, adhering to Data Protection legislation at all times.



Qualifications

A minimum of three GCSE?s grades A-C including Mathematics and English or Equivalent



Skills

Administrative experience with the demonstrable ability to work on own initiative and take ownership of allocated activities

Previous experience of working within a Human Resources environment

Previous experience of working with HR systems, and experience of using ResourceLink would be a distinct advantage

Experience of working in a large and complex organisation

Excellent IT skills and knowledge of Microsoft Office Packages specifically Word, Excel, and Teams

Good written and oral communication skills and numeracy skills

Strong customer service skills

The ability to manage conflicting priorities and work well under pressure

Demonstrable team working ethic and skills

A keen interest in Human Resources and an awareness of and/or willingness to learn about relevant employment legislation

Able to draft written correspondence, including contractual correspondence and emails, to a good standard

Ability to present information clearly and concisely using Microsoft Office packages

Able to deal sensitively with confidential information

Good interpersonal skills

Organised, methodical and accurate with excellent attention to detail

Demonstrable focus on continuous improvement

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